Imuran

What is Imuran?
	Please read our E-Book for complete treatment of autoimmune E-Book.

	Azathioprine (Imuran) -- Purine analog that decreases metabolism of purines and also may inhibit DNA and RNA synthesis. Reduces disability and symptoms of CIDP by suppressing immune-mediated damage to nerves. Initial dose: 50 mg PO qd, increased gradually to total daily dosage of 2-3 mg/kg/d PO Therapeutic dose of azathioprine difficult to determine for each patient; some evidence suggests that elevations of RBC volume (MCV) indicate therapeutic dosing Therapeutic response may take >6 mo to become apparent Side effects Can lead to various GI symptoms and ulcer formation with delayed healing (use with prophylactic agent to prevent ulcers); can lead to severe leukopenia, anemia, and thrombocytopenia (strictly monitor blood counts: obtain CBC count before treatment, every 1-2 wk for first few months, then monthly; in author's practice, WBC count of 3000/mL considered warning, requiring closer monitoring of WBC counts and infection precautions; 2000/mL considered sign to stop medication) As immune suppressant, places patients at risk for infections Monitor hepatic enzymes because of risk of liver failure (same frequency as monitoring of CBC count); caution should be used if new elevation of liver enzymes up to twice normal level noted; if stopping drug brings liver enzymes back to normal, drug can be tried again at later date, although with special caution; an idiosyncratic reaction can occur within days of initiation of treatment, including fever, jaundice, nausea and vomiting, and elevation of hepatic enzymes Discontinuation of drug usually results in complete resolution of symptoms; restarting drug does not always result in same reaction but should be considered carefully Please read the autoimmune E-Book for permanent treatment guidelines. Chronic fatigue syndrome Autoimmune autism Mercury linked autism Immunity in autism PCR Testing for Mycoplasma and Chlamydia in CFS/MCS Erectile Dysfunction, High Blood Pressure Linked Quranic Shifa Backpain Fibromyalgia Personality Electrical Stimulation Therapy Addison Estrogen DNA Magnets and ageing Heart solution Immunodeficiency Immunoglobulins Vaccination Sexual disorders Clinic Parkinson Clinic Epilepsy Clinic Pain Clinic Bone disorders clinic Joint disorder clinic Skin repair clinic Gene Manipulation Neurology Clinic TMJ CLINIC	Safe Hair Color Stem cells SLE & GENES Toxic Baby Car Seats Toxic Pesticide Under active thyroid Reading disorders Oral Polio Vaccine Reading disorders Best New Diet DHEA Fountain of Youth Magnets to tone face Younger Melbourne Avoid an episiotomy Celiac Disease Spice Names transplant treatment DiabeticTreatment Bay Leaves More Spices 7 Habits of Covy MagneticFieldMap NanoMedicine managed Care MS GENES Polymyalgia Achalasia u stay young Auto Autoimmune info Autoimmune-4 Autoimmune-5 Autoimmune anemia Autoimmune inflammation Autoimmune Ear Autoimmune Thyroid Autoimmune muscle Autoimmune diseases Autoimmunity Autoimmunity-2 Autonomic Quranic Shifa Mercury in makeup Toxic Lipstick
	www.cidpusa.org www.cidpusa.org/P/ivig.htm http://www.cidpusa.org/disease.html http://www.cidpusa.org/Lahore.html