Autoimmune
Diseases & Chronic
Inflammatory Demyelinating Polyradiculoneuropathy
Chronic inflammatory demyelinating
polyneuropathy (CIDP) is a neurological disorder
characterized by slowly progressive weakness and a loss
of sensation in the legs and arms. CIDP is more common
in young adults, and it affects men more than women.
Symptoms include tingling or numbness (beginning in the
toes and fingers); weakness of the arms and legs; aching
pain in the muscles; loss of deep tendon reflexes;
fatigue; and abnormal sensation. CIDP is similar to
Guillain-Barré syndrome, which appears suddenly and
generally improves spontaneously. Although CIDP was once
called "chronic Guillain-Barré syndrome," it is now
regarded as a related, but distinct condition.
The
course of CIDP varies widely among individuals. Some may
have a bout of CIDP followed by spontaneous recovery,
while others may have many bouts with partial recovery
in between relapses. The disease is a potentially
treatable cause of inflammatory neuropathy and
initiation of early treatment to prevent loss of nerve
cells is recommended. However, some individuals may
experience residual numbness or weakness.
SYMPTOMS AND SIGNS
(Not all symptoms and signs may be present.)
- Fatigue
- Loss of reflexes
- Tingling
- Numbness
- Pain
- Weakness
- Paralysis
