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We are hearing about a number of people getting the
following problems. A rash followed by sudden onset of weakness in
the legs diagnosed as Guillan Barred or Transverse Myelitis. Some
call it post infectious demyelination. The true cause OF THE
DISEASES is autoimmune
disease. We are hearing about
people getting on plasmapheresis and steroids and not recovering. It
takes longer to see a result from steroids.
Recently we have also heard from a women after getting a flu shot
she then developed weakness. The condition was correctly diagnosed as Guillian Barre Syndrome
but treatment was delayed . Soon after getting IVIg her
condition improved.
If the person gets
comatose after a viral infection, flu or vaccination then they have
developed a autoimmune Demyelinating condition in the Brain. This
may be called by many different names. A.D.E.M. (acute
Demyelinating enceplomyelitis), Bickerstaff encephalitis.
Mainly happens in children and young adults . Need to remember that
there is treatment available. Otherwise the mortality rate is high.
Here are some articles :
Vaccination and autoimmunity-'vaccinosis': a
dangerous liaison?
Shoenfeld Y, Aron-Maor A.
Department of Internal Medicine B, Sheba Medical Center, Tel
Hashomer, Israel. shoefel@post.tau.ac.il
The question of a connection between vaccination and autoimmune
illness (or phenomena) is surrounded by controversy. A heated debate
is going on regarding the causality between vaccines, such as
measles and anti-hepatitis B virus (HBV), and multiple sclerosis
(MS). Brain antibodies as well as clinical symptoms have been found
in patients vaccinated against those diseases. Other autoimmune
illnesses have been associated with vaccinations. Tetanus toxoid,
influenza vaccines, polio vaccine, and others, have been related to
phenomena ranging from autoantibodies production to full-blown
illness (such as rheumatoid arthritis (RA)). Conflicting data exists
regarding also the connection between autism and vaccination with
measles vaccine.So far only one controlled study of an experimental
animal model has been published, in which the possible causal
relation between vaccines and autoimmune findings has been examined:
in healthy puppies immunized with a variety of commonly given
vaccines, a variety of autoantibodies have been documented but no
frank autoimmune illness was recorded. The findings could also
represent a polyclonal activation (adjuvant reaction). The mechanism
(or mechanisms) of autoimmune reactions following immunization has
not yet been elucidated. One of the possibilities is molecular
mimicry; when a structural similarity exists between some viral
antigen (or other component of the vaccine) and a self-antigen. This
similarity may be the trigger to the autoimmune reaction. Other
possible mechanisms are discussed.Even though the data regarding the
relation between vaccination and autoimmune disease is conflicting,
it seems that some autoimmune phenomena are clearly related to
immunization (e.g. Guillain-Barre syndrome).The issue of the risk of
vaccination remains a philosophical one, since to date the
advantages of this policy have not been refuted, while the risk for
autoimmune disease has not been irrevocably proved. We discuss the
pros and cons of this issue (although the temporal relationship
(i.e. always 2-3 months following immunization) is impressive).
Copyright 2000 Academic Press.
Publication Types:
PMID: 10648110 [PubMed - indexed for MEDLINE]
Consequence or coincidence? The occurrence,
pathogenesis and significance of autoimmune manifestations after
viral vaccines.
Schattner A.
Department of Medicine, University of Cambridge, School of Clinical
Medicine, Level 5, Addenbrooke's Hospital, Hills Road, Cambridge CB2
2QQ, UK.
BACKGROUND:: Viruses and virus-induced lymphokines may have an
important role in the pathogenesis of autoimmunity (Schattner A.
Clin Immunol Immunopathol; 1994). The occurrence and significance of
autoimmune manifestations after the administration of viral vaccines
remain controversial. METHODS:: Medline search of all relevant
publications from 1966 through June 2004 with special emphasis on
search of each individual autoimmune manifestation and vaccination,
as well as specifically searching each viral vaccine for all
potential autoimmune syndromes reported. All relevant publications
were retrieved and critically analyzed. RESULTS:: The most
frequently reported autoimmune manifestations for the various
vaccinations, were: hepatitis A virus (HAV) - none; hepatitis B
virus (HBV) - rheumatoid arthritis, reactive arthritis, vasculitis,
encephalitis, neuropathy, thrombocytopenia; measles, mumps and
rubella vaccine (MMR) - acute arthritis or arthralgia, chronic
arthritis, thrombocytopenia; influenza - Guillain-Barre syndrome (GBS),
vasculitis; polio - GBS; varicella - mainly neurological syndromes.
Even these 'frequent' associations relate to a relatively small
number of patients. Whenever controlled studies of autoimmunity
following viral vaccines were undertaken, no evidence of an
association was found. CONCLUSIONS:: Very few patients may develop
some autoimmune diseases following viral vaccination (in particular
- arthropathy, vasculitis, neurological dysfunction and
thrombocytopenia). For the overwhelming majority of people, vaccines
are safe and no evidence linking viral vaccines with type 1
diabetes, multiple sclerosis (MS) or inflammatory bowel disease can
be found.
PMID: 15917108 [PubMed - in process]
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