The report, from researchers at
Oxford and the University of Exeter in
England, is said to be the first
evidence that a child’s sex is
associated with a mother’s diet.
Although sex is genetically determined
by whether sperm from the father
supplies an X or Y chromosome, it
appears that a mother’s body can favor
the successful development of a male or
female embryo.
The study, published in the journal
Proceedings of the Royal Society B:
Biological Sciences, shows a link
between higher energy intake around the
time of conception and the birth of
sons. The difference is not huge, but it
may be enough to help explain the
falling birthrate of boys in
industrialized countries, including the
United States and Britain.
The reason food intake may influence
the development of one sex of infant
rather than another isn’t fully
understood. However, in vitro
fertilization studies show that high
levels of glucose encourage the growth
of male embryos while inhibiting female
embryos.
It may be that male embryos are less
viable in women who regularly limit food
intake, such as skipping breakfast,
which is known to depress glucose
levels. A low glucose level may be
interpreted by the body as indicating
poor environmental conditions and low
food availability, the researchers said.
The data is based on a study of 740
first-time pregnant mothers in Britain
who didn’t know the sex of their fetus.
They provided records of their eating
habits before and during the early
stages of pregnancy, and researchers
analyzed the data based on estimated
calorie intake at the time of
conception. Among women who ate the
most, 56 percent had sons, compared with
45 percent among women who ate the
least. As well as consuming more
calories, women who had sons were more
likely to have eaten a higher quantity
and wider range of nutrients, including
potassium, calcium and vitamins C, E and
B12. There was also a strong correlation
between women eating breakfast cereals
and producing sons.
The data are limited by the fact that
they are based on self-reported food
intake, which can be unreliable.
However, the consistency of the trend
offers an explanation for the small but
consistent decline in the proportion of
boys born in industrialized countries
over the last 40 years, where even
though women in general appear to be
consuming more, eating habits have
changed.
In the United States, for instance,
the proportion of adults eating
breakfast fell from 86 percent to 75
percent between 1965 and 1991. And
although women may be be eating more
overall, a nutrient-poor diet could be
less favorable to a male fetus. Glucose
levels may also fluctuate in women who
are dieting and trying to lose weight
prior to pregnancy. In animals, more
sons are produced when a mother ranks
high in the group or has plentiful food
resources.