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Welcome to the treatment section of the CIDPUSA Foundation  

   Look at our E-BOOK contents to stay healthy permanently. to prevent diseases.   Printer Friendly Page 
  
    Guide to treatment of autoimmune diseases.

 The treatment for all the autoimmune diseases is similar. These diseases are caused by inflammation, triggered by bacteria, viruses or chemicals. To reduce inflammation. You can choose drugs or non drugs (herbal, homeopathic or natural) treatments. The cornerstone for treatment in the past has been steroids which are fast out the door due to their side effect profile. However if use steroids on alternate days and in small doses they still can provide adequate treatment. If people get one red eye it is almost always due to inflammation and quickly responds to steroid drops in a day. Autoimmune ear disease responds quickly to steroids placed in the inner ear. But intravenous steroids will help too

 

 

. Oral steroids cause many side effects so should only be used for a short time. Steroids will stop the inflammatory attack but then one has to uncover the reason for the attack the protein, virus, bacteria (mycoplasma)! In every autoimmune disease a foreign protein antigen is triggering the disease it need to be indentified and removed all these details you will find in the disease pages or the Flame within E-Book.

             Begin treatment with diet modifications described in the diet chapter. The next step will be to avoid toxins. If the disease was caused by exposure to diesel fumes then the patient should avoid them.  Avoid pesticides if you are a farmer in New Zealand  spraying your field and you can smell the toxin, they end up getting CIDP or Parkinsons. A farmer in Bangladesh and Northern India is exposed to high Arsenic exposure in the ground water. The high arsenic is brought about by excessive pesticide usage. This will cause and trigger many autoimmune diseases. The farmers in Vietnam are exposed to the deadly agent orange used in the Vietnam Era wars.

The next step in medications is supplements like vitamin-D, vitamin B-12, Folate, Thiamine, B-6 (careful with B-6)) they are usually available in a sublingual  tablet. If you read our e-book you see we recommend foods as alternative to these vitamins. The vitamins help overcome many problems like in celiac disease there is always a Vitamin B-12 and iron deficiency. People with Sjogrens have a B-12 deficiency.

Steroids are the fasted acting drug will bring in quick recovery then other treatments can be used. IVIg brings a very fast recovery in Kawasaki disease, CIDP, GBS if used very early in the treatment. IVIg will help MS, myasthenia. Many patients with Myasthenia have responded to Thymectomy because in Myasthenia often there are tumors of the thymus. Steroids reduce inflammation quickly and for short peroid are excellent treatment but if you prefer long term natural treatment use Omega-3 Fatty acids which reduce inflammation.

Before trying any drugs, please try a different diet, all people should shift to a gluten free diet please see the celiac section for advice. Again everyone should give up milk unless it is non pasteurized milk. We recommend a total vegetarian diet mainly brown rice, potatoes and fresh fruit juices, salads. All your diet should be fresh and no processed foods like chips.

 

Intravenous immune globulin (IVIG) has also been found to be beneficial. in CIDP treatment. IVIG is usually given in divided doses over 4 or 5 consecutive days at a  total dose of 2g/kg.  If the total infusion can be given in two large doses it works better for the patient. It is recommended that for all the neurological disorders the dose of IVIg should be 2gm/kg. The cost and procedure of IVIg is cumbersome many of our patients have improved simple by alternatives no IVIg involved. These alternatives are described in the E-Book in its third edition and a treasure.

 

 

Maintenance doses of IVIg are often needed at monthly intervals to maintain clinical response. Serious side effects of IVIG treatment include, (fatal anaphylaxis in IgA-deficient patients seen in {In patients who have anti IgA  antibodies}.  I recommend that before the infusion the total IgA level be measured. If the level is below 58 then anti IgA ANTIBODIES NEED TO BE MEASURED. However a case has been reported with IgA LEVEL of 58 who later developed IgA reaction. So a careful history should be taken of all patients first starting IVIg. If the lab reports IgA <20 IT MAY BE SAFE TO ASSUME THAT IT IS ZERO. Not Always. Check the patients history! ( Who is your IVIg PROVIDER)? Learn to give IVIg safely, learn the secrets!

 Potential nephrotoxicity (renal failure) risk from IVIg exists, especially in patients with pre-existing renal disease. FDA issued this advisory when lots of patients developed nephrotoxicity. FDA also issued recalls after Hepatitis was induced after the use of IVIg. This led to a nationwide IVIg shortage. A nurse from a prominent IVIg company contacted us and informed us that when she was administering IVIg she noticed a yellowish discoloration , she said that she did not want to infuse the product however she did. The patient spent 6 days in the hospital with a terrible headache (aspetic meningitis). Then the patients physical condition was weak. The risk is there and there are simpler ways to treat Multiple Sclerosis so please read our e-book and follow the treatment protocols.

 

For patients  resistant to IVIg therapy one needs to check if the dose being given is correct. If the dose has been 2g/kg then one can consider alternate with steroids and IVIg.  If that does not work then Cyclophosphamide, Rituxan, Cyclosporin can be considered.

IVIg is used as a rescue therapy or first line agent and then a second line agent is started like cyclosporin. In time this becomes the agent of choice for chronic maintenance.

For very simple treatment of your autoimmune disorder which can be done with a oral course of medication available any part of planet earth see the Flame within contents. The modern biological treatments are a wonder and have helped people with arthritis and vasculitis. Stem cell treatments have helped many people but they are cumbersome and expensive. Your life span may be reduced by stem cell transplant.

Have any questions or need help then please see services section

 

 
Neurology. 1998 Dec;51(6 Suppl 5):S16-21.  

Treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulin.

Hahn AF. University of Western Ontario, London Health Sciences Centre, Canada.

 IVIg, therapeutic plasma exchange (PE), and prednisone, are of proven benefit. Comparative studies indicate that IVIg and PE confer equal short-term benefit. Efficacy of IVIg is maintained; regularly timed pulse treatments may stabilize relapsing CIDP. The combination of IVIg and prednisone may be advantageous in long-term management. Despite the high cost, IVIg is considered the preferred first treatment. The safety profile is similar to that reported for other conditions; close monitoring during the infusion is recommended.
 
Neurology. 2002 Dec 24;59(12 Suppl 6):S33-40.  
 
Intravenous gammaglobulin (IVIg) for treatment of CIDP and related immune-mediated neuropathies.

Brannagan TH 3rd.
 Department of Neurology and Neuroscience, Weill Medical College of Cornell NYC

Intravenous immune globulin (IVIg) is considered an effective and safe treatment for autoimmune neuropathies, especially in comparison to the alternative treatments such as corticosteroids, chemotherapy, and plasmapheresis. .

To conclude, CIDP is a very variable condition. It is auto-immune and is treatable. It is exceptional for CIDP not to respond to at least one of the available drugs. The first choice of treatment is either prednisolone or IVIg. The diagnosis is difficult, much less so than GBS, depending critically on the nerve conduction studies and neuro-physiologies. Trials for immuno-suppression have shown promise. ..........

 
 
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