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What Happens When the Brainís Immune System is Activated?

The brainís immune system cells, once activated, begin to move about the nervous system, secreting numerous immune chemicals (called cytokines and chemokines) and pouring out an enormous amount of free radicals in an effort to kill invading organisms. The problem is--there are no invading organisms. It has been tricked by the vaccine into believing there are.

Unlike the bodyís immune system, the microglia also secrete two other chemicals that are very destructive of brain cells and their connecting processes. These chemicals, glutamate and quinolinic acid, are called excitotoxins. They also dramatically increase free radical generation in the brain. Studies of patients have shown that levels of these two excitotoxins can rise to very dangerous levels in the brain following viral and bacterial infections of the brain. High quinolinic acid levels in the brain are thought to be the cause of the dementia seen with HIV infection.

The problem with our present vaccine policy is that so many vaccines are being given so close together and over such a long period that the brainís immune system is constantly activated. This has been shown experimentally in numerous studies. This means that the brain will be exposed to large amounts of the excitotoxins as well as the immune cytokines over the same period.

Studies on all of these disorders, even in autism, have shown high levels of immune cytokines and excitotoxins in the nervous system. These destructive chemicals, as well as the free radicals they generate, are diffused throughout the nervous system doing damage, a process called bystander injury. Itís sort of like throwing a bomb in a crowd.

Not only will some be killed directly by the blast but those far out into the radius of the explosion will be killed by shrapnel.

Normally, the brainís immune system, like the bodyís, activates quickly and then promptly shuts off to minimize the bystander damage. Vaccination wonít let the microglia shut down. In the developing brain, this can lead to language problems, behavioral dysfunction and even dementia.

In the adult, it can lead to the Gulf War Syndrome or one of the more common neurodegenerative diseases, such as Parkinsonís disease, Alzheimerís dementia or Lou Gehrigís disease (ALS).

A recent study by the world-renowned immunologist Dr. H. Hugh Fudenberg found that adults vaccinated yearly for five years in a row with the flu vaccine had a 10-fold increased risk of developing Alzheimerís disease. He attributes this to the mercury and aluminum in the vaccine. Interestingly, both of these metals have been shown to activate microglia and increase excitotoxicity in the brain.

Direct Effect of the Cytokines

Various cytokines have been used to treat cancer patients as well as other common diseases.

Studies of the effects of these cytokines on brain function reveal some very close parallels to the diseases we have been discussing. For a more in-depth study of these effects I suggest you read my article appearing in the Journal of the American Nutriceutical Association (volume 6 [fall], Number 4, 2003, pp 21-35) and in the summer issue 2004 of the Journal of the American Association of Physicians and Surgeons.

One can see:

  • Confusion
  • Language difficulties
  • Disorientation
  • Seizures
  • Memory problems
  • Somnolence
  • Low-grade fevers
  • Irritability
  • Mood alterations
  • Combativeness
  • Difficulty concentrating
  • A host of other behavioral problems

In the child, brain immune over-activation has been shown to be particularly damaging to the amygdala and other limbic structures of the brain. This can lead to unusual syndromes such as the loss of "theory of mind" and " Alice in Wonderland syndrome." It has also been shown to damage the executive functions of the frontal lobes.

In essence, what is lost is that which makes us social human beings, able to function in a complex world of ideas and interactions.

Several studies have indeed shown elevated levels of cytokines in autistic children. It is also interesting to note that these cytokines, especially interleukin-1Ŗ and tumor necrosis factor-alpha (TNF-a) dramatically increase the damage produced by excitotoxins. So, what we see is a viscous cycle of immune activation, excitotoxin and cytokine excretion, and free radical production. The latter starts the cycle all over again. .