|In primary biliary cirrhosis (PBC) the bile ducts in the
liver are attacked by the bodys own immune system.|
Bile ducts are tiny tubes in the liver that remove bile and send it to the gallbladder, . Bile usually works to break up the fat in food into small droplets, and helps the body to absorb vitamins A, D, E and K from our diet, so it plays an important part in digestion.
When the bile ducts are attacked, they are damaged and swell, and cannot carry out these functions properly. It also means that toxic (poisonous) substances, which are normally excreted from the body through the bile, are instead kept inside the liver. These substances, such as bile acids and minerals, lead to further damage to the bile ducts and the liver tissue.
The liver can normally heal itself without scarring, but if the damage is continuous and severe, the regrowth process goes wrong and scarring occurs, meaning the liver cannot function properly. This severe damage is known as cirrhosis.
Despite its name, not everybody with primary biliary cirrhosis actually progresses to cirrhosis, because this condition often happens very slowly and with no symptoms for years.
Cirrhosis is not always, as is often assumed, related to the over-consumption of alcohol. It often has quite different causes such as inherited liver diseases. However, those with PBC can often not tolerate alcohol because their liver no longer processes it properly.
Primary biliary cirrhosis is a cholestatic condition (tending to diminish or stop the flow of bile). Because the bile can no longer break down fatty substances fully, it is frequently associated with high levels of cholesterol in the blood, which can be a risk factor for heart disease, and may lead to liver failure. Because the liver cannot carry out its usual functions, there are many other potential complications such as osteoporosis.
Women are nine times more likely than men to have this condition, and it most commonly appears between the ages of 30 and 60.
Symptoms of primary biliary cirrhosis include:
Extreme tiredness, Itchiness (pruritus), Lack of appetite. Nausea, Joint or bone pain. Arthritis. Pain over the liver (the upper right hand side below the ribs).
Skin changes such as blotchiness, or jaundice (when the skin and
the whites of the eyes turn a yellowish colour). Dryness in the
mouth or eyes . Diarrhea, Sometimes there are no symptoms,
especially if it is mild PBC may be discovered accidentally, for
example during a routine blood test.
When symptoms of primary biliary
cirrhosis are presented to a doctor, the first step in diagnosis is
often a blood test for a substance called AMA (Anti-mitochondrial
Antibody). This antibody is a substance produced by the
disease-fighting system of the body and around 95% of those with PBC
will test positive for this antibody.
Treatment:& Alternative treatments
Complete cure for primary biliary
cirrhosis is by alternative medicine but the following therapies can have some effect in
managing the condition:
In alternative treatments use of Garlic daily can reverse this condition. Better to use a pickled Garlic.
Homepathic treatment is with Lycopodium is a excellent treatment will not only prevent but also reverse the disease.