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Yeast infections occur less frequently in patients treated with antibiotics if bowel tolerance doses of ascorbic acid are simul- taneously used. Ascorbic
acid seems to reduce the systemic toxicity considerably but does not eliminate the primary infection. It has been helpful to patients with allergic problems secondary to candida.
Vitamin-C or ascorbate use in many disease
Although ascorbic acid should be given in some form to all sick patients to help meet the stress of disease, it is my experience that ascorbate has little effect on the primary fungal infections. Systemic toxicity and complications can be reduced in incidence. It may be found that appropriate antifungal agents will better penetrate tissues saturated in ascorbate.
TRAUMA, SURGERY, AND BURNS
Swelling and pain from trauma, surgery, and burns are markedly reduced by bowel tolerance doses of ascorbic acid. Doses should be given a minimum of 6 times a day for trauma and surgery. Burns can require hourly doses. Serious burns, major trauma, and surgery should be treated with intravenous ascorbate. The effect of ascorbate on anesthetics should be studied. Barbiturates and many narcotics are blocked, (26) so their use as anesthetic agents will be limited when ascorbate is used during surgery. While practicing orthopaedic surgery, I had some experience with trauma cases in which I used ascorbic acid post-operatively. There was virtual elimination of confusion in elderly patients following major surgeries such as with hip fractures when ascorbate was given. This confusion is commonly ascribed to fat embolization and the subsequent inflammation provoked in the tissues by the emboli. I did several menisectomies where one knee had been done before vitamin C was used, and the other side after vitamin C was used. The pain and post-operative recovery time were lessened considerably. The amount of inflammation and edema following injury and surgery were markedly reduced. The pain medications used were relatively minimal. My limited experience in replacing skin flaps avulsed by trauma indicated a whole degree of lessened difficulties with much greater success.
Anyone who has done animal surgery other than on humans is impressed by the rapid recovery rate. Humans loaded with ascorbate would appear to recover similarly to the animals which make their own ascorbate in response to stress. In the past, vitamin C administered to patients in hospitals post-operatively has been in trivial amounts never exceeding several grams. I predict that reimplantations of major amputations, even transplant surgeries, and especially fine surgeries of the eyes, ears, or fingers will enjoy a phenomenal increase in success rate when ascorbate is utilized in doses of 100 grams or more per 24 hours.
The limited stress-coping mechanisms of humans seems to be the result of rapid ascorbate depletion. With surgery this leads to vascular thrombosis, hemorrhage, infection, edema, drug reactions, shock, adrenal collapse with limited adrenaline and steroid production, etc.
I have avoided the treatment of cancer patients for legal reasons; however, I have given nutritional consults to a number of cancer patients and have observed an increased bowel tolerance to ascorbic acid. Were I treating cancer patients, I would not limit their ascorbic acid ingestion to a set amount but would titrate them to bowel tolerance. Ewan Cameron's advice against giving cancer patients with widespread metastasis large amounts of ascorbate too rapidly at first should be heeded. He found that sometimes extensive necrosis or hemorrhage in the cancer could kill a patient with widespread metastasis if the vitamin was started too rapidly (16). Hopefully, in the future ascorbic acid will be among the initial treatments given cancer patients. The additional nutritional needs of cancer patients are not limited to ascorbic acid, but certainly the stress involved with having the disease depletes ascorbate levels in the body. Ascorbate should be used in cancer patients to avert disorders of ascorbate deficiency in various systems of the body including the immune system.
BACK PAIN FROM DISC DISEASE
Greenwood (27) observed that 1 gram a day would reduce the incidence of necessary surgery on discs. At bowel tolerance levels, ascorbic acid reduces pain about 50% and lessens the difficulties with narcotics and muscle relaxants (2). It is not, however, the only nutritional support that patients with back pain should receive.
Bowel tolerance is not increased by degenerative arthritis although occasionally ascorbate has some beneficial effect.
Ankylosing spondylitis and rheumatoid arthritis do increase tolerance. Clinical response varies. Norman Cousins (28) curing his own ankylosing spondylitis with ascorbate is not unexpected. With these and other collagen diseases, food and chemical allergies can sometimes be found. It may be that the blocking of allergic reactions with augmented adrenal function is one of the reasons these patients are sometimes benefitted.
Three cases with typical sandpaper-like rash, peeling skin, and diagnostic laboratory findings of scarlet fever have responded within an hour or overnight. I think this immediate response is due to the neutralization of the small amount of streptococcus toxin responsible for the disease. Although I have not seen a case of acute rheumatic fever, I would anticipate rapid effects.
HERPES: COLD SORES, GENITAL LESIONS, AND SHINGLES
Acute herpes infections are usually ameliorated with bowel tolerance doses of ascorbic acid. However, recurrences are common especially if the disease has already become chronic. Zinc in combination with ascorbic acid is more effective for herpes; however, caution and regular monitoring of patients on zinc should be done.
For chronic herpes, intravenous ascorbate may also be of benefit.
CRIB DEATHS (SUDDEN INFANT DEATH SYNDROME)
I would agree with Kalokerinos (22) and Klenner (8) that crib deaths are often caused by sudden ascorbate depletions. The induced scI would agree with Kalokerinos (22) and Klenner (8) that crib deaths are often caused by sudden ascorbate depletions. The induced scurvy in some vital regulatory center kills the child. This induced deficiency is more likely to occur when the diet is poor in vitamin C. All of the epidemiologic factors predisposing to crib deaths are associated with low vitamin C intake or high vitamin C destruction.
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