Lower back pain and bladder dysfunction

A 36 year old man presented with progressive low back pain and bladder dysfunction. He had had periods of non-specific back pain for more than a year. In the past two weeks the pain had got worse, radiating from the left dorsolateral thigh to the lateral site of his left foot. For three days he had had difficulties initiating micturation, and the flow had weakened. He felt numb sensations in the left scrotum, the perineal region, and on the lateral site of the left foot. He also noticed muscle weakness in the left foot. He had no history of trauma or recent disease.

General physical examination indicated a healthy young man. Neurological examination showed paralysis of the left foot extensors, motor weakness of left foot flexors (grade 2-3), and sensory deficits from the medial leg to the dorsal lateral foot. The patellar reflexes were vivid on both sides (left more than right). The ankle jerk was absent on both sides and plantar flexes indifferent. Rectal examination indicated saw saddle anaesthesia and low sphincter tone. Normal and crossed straight leg raising tests were positive at 50° at the left side.

Questions

(1) What worries you most in this case?

(2) What is the term for this complex of symptoms?

(3) What is the differential diagnosis?

(4) What would you do next for this patient?

(5) What are the features seen in the magnetic resonance image (figure¹)?

 

Sagittal T2 weighted magnetic resonance image showing the lumbar spine

 

(6) What is the diagnosis?

(7) How should you manage this case?

Answers

(1) Alarms should go off when a patient presents with difficulties in urine and sensory loss in the buttock region. Other warning signs are the decreased sphincter tone and the motor and sensory loss in the left leg accompanied by acute worsening of backache.

(2) Cauda equina syndrome is caused by narrowing of the spinal canal: nerve roots become trapped and start to dysfunction. The array of symptoms can guide the investigator to the level of compression.

(3) All conditions resulting in compression can explain cauda equina syndrome. Consider trauma, disc herniation, spinal stenosis, neoplasms, spondylolisthesis, inflammatory conditions, and iatrogenic conditions.

(4) Start by taking an accurate history and a clinical examination to narrow the differential diagnosis. You should already suspect the diagnosis of central disc prolapse. Magnetic resonance imaging is the best diagnostic investigation because it can depict soft tissues. Consult the orthopaedic or neurological surgeon immediately for further treatment.

(5) The magnetic resonance image in the figure¹ shows a massive herniated disc at the level of L4-L5 into the spinal canal. This view also shows some bulging of the disc at the level of L3-L4 and minor discopathy in the adjacent levels.

(6) Cauda equina syndrome to central disc prolapse at the level of L4-L5.

(7) The suspected diagnosis of central disc prolapse causing cauda equina syndrome is an investigative and surgical emergency. Surgical decompression should be performed as soon as possible to stop further neurological loss and improve clinical outcome. 1 2 3. The preferred method of decompression is laminotomy and partial discectomy.

Discussion

Low back pain is one of the main reasons for a visit to a general practitioner. More than 95% of patients who have low back pain have a benign musculoskeletal pain syndrome; the pain is a manifestation of a more serious pathology in only 5%. Central disc prolapse causing cauda equina syndrome is only present in 2% of all cases of a herniated lumbar disc and in only 0.04% of all patients with low back pain.

Herniation of an intervertebral disc is generally the result of degeneration of the disc. The inner nucleus herniates through the ruptured outside (annulus fibrosus) of the disc. The herniated tissue causes compression of dorsal roots in the spinal canal, which can result in pain, changed reflexes, and sensory and motor loss. The level of the herniation relates to the symptoms (table). In most cases lumbar herniations are at the level of L4-L5 or L5-S1. Herniation of the intervertebral disc mainly affects men aged 40-50.

Nerve Root	Pain	Sensory deficit	Motor deficit	Reflex deficit
L2	Anterior medial thigh	Upper thigh	Slight quadriceps weakness; hip flexion; thigh adduction	Slightly diminished suprapatellar
L3	Anterior lateral thigh	Lower thigh	Quadriceps weakness; knee extension; thigh adduction	Patellar or suprapatellar
L4	Posterolateral thigh, anterior tibia	Medial leg	Knee and foot extension	Patellar
L5	Dorsum of foot	Dorsum of foot	Dorsiflexion of foot and toes	Hamstrings
S1-2	Lateral foot	Lateral foot	Plantar flexion of foot and toes	Achilles
S3-5	Perineum	Saddle	Sphincters	Bulbocavernosus; anal

The rare diagnosis of cauda equina syndrome secondary to central disc prolapse is made on suspicion. Most patients complain of unilateral or bilateral leg pain and numbness in the perineum or leg or both.The most sensitive (0.90) and specific (0.95) finding is urinary retention or, later, even incontinence.Saddle anaesthesia and decreased sphincter tone on rectal examination, with sensitivities of 0.75 and 0.6-0.8, make the diagnosis even more plausible.Lasègue’s straight leg test, which will cause pain by elongating the nerve root by passive flexion of the hip in a supine patient, is not very sensitive in this case. Onset can be gradual, as in this man, or sudden with acute trauma related sciatic pain and problems with vesicular control.Unlike most other back problems it may even be painless.

The man had a partial laminotomy, and discectomy at the level of L4-L5 was successfully performed six hours after initial admission. He was discharged after four days, and apart from minimal sensory loss of his left foot he had no complaints at three months’ follow up.

Competing interests: None declared.

Provenance and peer review: Not commissioned; externally peer reviewed.

Aernout R J Langeveld orthopaedic resident ¹Department of Orthopaedic Surgery, Vrije Universiteit, University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands
Johannes L Bron orthopaedic resident ¹Department of Orthopaedic Surgery, Vrije Universiteit, University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands
Annemieke J E de Bruijn radiologist ²Department of Radiology, Deventer Ziekenhuis, Fesuvurstraat 7, 7415 CM Deventer, NetherlandsCorrespondence to: A R J Langeveld
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