TAIPEI, Taiwan -- A new autoimmune treatment for
brain tumors has been developed by the
Taichung-based China Medical University Hospital
(CMUH), with a superior survival rate of 85.8
percent, hospital sources said yesterday.
CMUH Neurosurgery Department Director Cho Der-yang
explained that the new therapy employs dendritic
cells extracted from a patient's blood to fight
malignant gliomas cells in the brain -- both to
minimize side effects and increase the chances
of survival.
Cho further explained that the dendritic
cells extracted are first cultivated in vitro
along with malignant gliomas cells, a process
that induces dendritic cells to better
understand their enemy and trigger the immune
mechanism against this type of tumor cell.
The "educated" dendritic cells are then
injected back into the patient to stimulate his
human T-lymphocytes, which will then turn on the
remaining brain tumor cells or malignant gliomas
cells.
"A single course of treatment takes six
months and 10 injections of cultivated dendritic
cells," Cho added.
In previous clinical experiments, among the
21 volunteers with malignant gliomas, 18
survived the observation period of up to 32
months and only three died during the course,
representing a three-year survival rate of 85.8
percent.