AUTOIMMUNE DISEASES IN DOGS CATS, pets

Though there is a slight difference in animals and humans but in general they have the same organ systems. The physiological mechanisms are very similar. Humans can be diverse in thought and have the most intelligent central nervous system. Animal may excel in Vision ability to see in the dark, ability to hear frequencies which humans cannot, ability to detect danger which we cannot. Ability to digest carbohydrates which we cannot.

The treatment of our pets is very similar to humans and the same drugs work. Our new autoimmune diseases e-book is a excellent guide for treatment on 101 autoimmune conditions.

Coming down to diseases animal suffer they same problems like humans and treatment is the same.. If you have any questions about your Pets health and autoimmune disease please contact us. The German Sheppard which fall down instead of attacking have Narcolepsy and can be treated.

The most common disease in Animals is AUTOIMMUNE DISEASE.

The anemia, seizures , arthritis are all autoimmune. Please read our E-Book for simple treatment guidelines.

J Peripher Nerv Syst. 1996;1(2):149-55.

Chronic inflammatory demyelinating polyneuropathy in dogs and cats.

Braund KG, Vallat JM, Steiss JE, Panangala VS, Zimmer PL.

Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Alabama, USA. braunkg@vetmed.auburn.edu

Over the past several years, we have accumulated data on a spontaneous demyelinating peripheral neuropathy that is not well identified in domestic animals. This disorder occurs in dogs and cats of either sex and does not appear breed-related. Onset of signs is usually insidious and the course is typically chronic, sometimes relapsing, and often slowly progressive. Mature animals of any age may be affected. Clinical signs include tetraparesis, sometimes progressing to tetraplegia, stumbling gait, and hyporeflexia. Motor nerve conduction velocities are decreased. Pathologically, changes in teased single fibers from peripheral nerves are dominated by multifocal paranodal demyelination. Scattered, thinly myelinated fibers are seen on semithin sections. Ultrastructural studies reveal macrophages within myelinated fibers stripping the myelin sheaths, naked and remyelinating axons, and focal/multifocal endoneurial mononuclear cells. Indirect immunofluorescence revealed positive IgG staining in peripheral nerve myelin sheaths from two dogs. The course of the disease, clinical signs, electrophysiology, and pathology have similarities to chronic inflammatory demyelinating polyneuropathy in people.

PMID: 10975723 [PubMed - indexed for MEDLINE]

Autoimmune hemolytic anemia

Anemia is a disease, with a decrease in the number of red blood cells (RBCs) , resulting in a decrease in the oxygen-carrying capacity of the blood. Anemia can be caused by blood loss, decreased production of new RBCs, or an increase in the rate of their destruction, known as hemolytic anemia. In primary hemolytic anemia, the RBCs can be attacked by autoantibodies, In secondary type drugs, infectious disease, cancer, parasites, or heavy metals , lead, and zinc have all been implicated as potential cause hemolytic anemia.

IVIG given early will stop the disease process and colostrum will also help as a supplemt.

Blood transfusions are rarely used. A foreign protein can increase the crisis .

Immune-mediated thrombocytopenia

ITP is the destruction of "thrombocytes" by the immune system in much the same manner as RBCs are destroyed in AIHA.

IVIg is FDA approved for ITP .

Autoimmune diseases of the skin

As a group, autoimmune diseases of the skin are increasing.

"Pemphigus is a group of autoimmune skin disorders characterized by vesicles and bullae in the mouth and at mucocutaneous junctions, those borders of haired skin and mucosal tissues. Areas include the eyelids, lips, nostrils, anus can be involved. pemphigus vegetans" are thick and irregular and proliferate into vegetative lesions marked by oozing and pustules. It is thought to be a more benign form of pemphigus vulgaris.

Pemphigus foliaceous is rarely found in the mouth or at mucocutaneous junctions.

IVIG is off label approved for Pemphigus. Medicare accepts the diagnose of pemphigus for IVIg treatment at home.

Systemic lupus erythematosis

The classic example of a multi-systemic autoimmune disease is systemic lupus erythematosis (SLE), also known as lupus. Often called the "great imitator, lupus can mimic nearly any other disease state. The signs of SLE may be acute (sudden onset) or chronic and are usually cyclic. A fluctuating fever that does not respond to antibiotics is one of the hallmark signs, as is a stiff gait or shifting lameness (polyarthritis, see below). Other signs may include a hemolytic anemia or thrombocytopenia, leukopenia (a low white blood count), or a symmetrical dermatitis, especially over the bridge of the nose ("butterfly lesion,").

Polyarthritis

Immune-mediated polyarthritis can be seen in SLE as above or as an independent finding. Several different specific diseases are included in this classification, but the major signs are all similar. A high fever, joint pain and swelling, and a lameness that seems to shift from leg to leg are typical findings. In some cases enlarged lymph nodes are found.

CIDP organization of USA.

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www.cidpusa.org www.cidpusa.org/P/ivig.htm http://www.cidpusa.org/disease.html http://www.cidpusa.org/Lahore.html