Lowering High Homocysteine With Diet
Coconut water, Saffron, Garlic & spinach

Homocysteine Lowering with Folic Acid and B
Vitamins in Vascular Disease.
Folic acid is also abundant in certain Southern comfort foods, notably rice, black-eyed peas, and turnip greens, parbroiled rice and dried peas better than fresh, but fresh greens better than canned or frozen. Rice, black-eyed peas, lentils, and greens are relatively low in calories (provided they are not served with oil, butter, or salted pork), and very useful in homocysteine-lowering prevention diet.
N Engl J Med 2006;354
Background In observational studies, lower homocysteine levels
are associated with lower rates of coronary heart disease and
stroke. Folic acid and vitamins B6 and B12 lower homocysteine
levels. Methods We randomly assigned 5522 patients 55 years of
age or older who had vascular disease or diabetes to daily
treatment either with the combination of 2.5 mg of folic acid,
50 mg of vitamin B6, and 1 mg of vitamin B12 or with placebo for
an average of five years. The primary outcome was a composite of
death from cardiovascular causes, myocardial infarction, and
stroke. Results Mean plasma homocysteine levels decreased by 2.4
micromol per liter (0.3 mg per liter) in the active-treatment
group and increased by 0.8 micromol per liter (0.1 mg per liter)
in the placebo group. Primary outcome events occurred in 519
patients (18.8 percent) assigned to active therapy and 547 (19.8
percent) assigned to placebo (relative risk, 0.95; 95 percent
confidence interval, 0.84 to 1.07; P=0.41). As compared with
placebo, active treatment did not significantly decrease the
risk of death from cardiovascular causes (relative risk, 0.96;
95 percent confidence interval, 0.81 to 1.13), myocardial
infarction (relative risk, 0.98; 95 percent confidence interval,
0.85 to 1.14), or any of the secondary outcomes. Fewer
patients assigned to active treatment than to placebo had a
stroke (relative risk, 0.75; 95 percent confidence interval,
0.59 to 0.97). More patients in the active-treatment group were
hospitalized for unstable angina (relative risk, 1.24; 95
percent confidence interval, 1.04 to 1.49). Conclusions
Supplements combining folic acid and vitamins B6 and B12 did not
reduce the risk of major cardiovascular events in patients with
vascular disease
